Blar i NTNU Open på forfatter "Rye, Philip D"
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Bi-functional alginate oligosaccharide–polymyxin conjugates for improved treatment of multidrug-resistant gram-negative bacterial infections
Stokniene, Joana; Powell, Lydia C.; Aarstad, Olav Andreas; Aachmann, Finn Lillelund; Rye, Philip D; Hill, Katja E.; Thomas, David W.; Ferguson, Elaine L. (Peer reviewed; Journal article, 2020)The recent emergence of resistance to colistin, an antibiotic of last resort with dose-limiting toxicity, has highlighted the need for alternative approaches to combat infection. This study aimed to generate and characterise ... -
Exploiting mannuronan C-5 epimerases in commercial alginate production
Tøndervik, Anne; Aarstad, Olav Andreas; Aune, Randi; Maleki, Susan; Rye, Philip D; Dessen, Arne; Skjåk-Bræk, Gudmund; Sletta, Håvard (Peer reviewed; Journal article, 2020)Alginates are one of the major polysaccharide constituents of marine brown algae in commercial manufacturing. However, the content and composition of alginates differ according to the distinct parts of these macroalgae and ...